Myasthenia Gravis: Brave the grave

 

 

Myasthenia Gravis is an autoimmune disorder that affects the neuromuscular junction, the point where nerves meet muscles. Age and sex no bar but it is more common in women under the age of 40 and men over the age of 60.

 

The most common symptoms of MG are muscle weakness and fatigue that worsen with activity and improve with rest. Common clinical presentations are drooping of the eyelids, double vision, difficulty chewing/swallowing, slurred speech, and shortness of breath.

 

 

 

 

 

The diagnosis of MG can be challenging as the symptoms are similar to other neurological conditions. A thorough medical history, clinical examination, and diagnostic tests such as blood tests (Acetylcholine receptor antibody/ MuSK antibody), Neostigmine test, SFEMG, RNST are necessary to confirm the diagnosis.

 

The treatment of MG includes medication, such as anticholinesterase inhibitors and immunosuppressive agents. In severe cases, PLEX or IVIg may be required. Physical and occupational therapies may help improve muscle strength and function. co-existing medical conditions should also be managed along side and common triggers like stress, infections, and certain medications be avoided

 

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